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  • Author Details
  • Competing Interests
    None declared
  • References
    1. Cutuli SL, See EJ, Osawa, EA, et al. Accuracy of non-invasive body temperature measurement methods in adult patients admitted to the intensive care unit: a systematic review and meta-analysis. Crit Care Resusc 2021; 23: 6-13.
    2. Yanase F, Cutuli SL, Naorungroj T, et al. Temperature and haemodynamic effects of a 100 mL bolus of 20% albumin at room versus body temperature in cardiac surgery patients. Crit Care Resusc 2021; 23: 14-23.
    3. Anstey JR, Forrest PR, Cass H, et al. Sustained normothermia in septic shock and the energy transfer required: a report of a pilot feasibility study using newer-generation surface cooling devices. Crit Care Resusc 2021; 23: 113-6.
    4. Young PJ. Turning up the heat on fever research? Crit Care Resusc 2021; 23: 4-5.
    5. Billot L, Bellomo R, Gallagher M, et al. The Plasma-Lyte 148 versus Saline (PLUS) statistical analysis plan: a multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality. Crit Care Resusc 2021; 23: 24-31.
    6. Winearls J, Wullschleger M, Wake E, et al. Fibrinogen Early In Severe Trauma studY (FEISTY): results from an Australian multicentre randomised controlled pilot trial. Crit Care Resusc 2021; 23: 32-46.
    7. Gibbons KS, Schlapbach LJ, Horton SB, et al. Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial. Crit Care Resusc 2021; 23: 47-58.
    8. Koulenti D, Armaganidis A, Arvaniti K, et al. Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units: the PneumoINSPIRE study. Crit Care Resusc 2021; 23: 59-66.
    9. Mochizuki K, Fujii T, Paul E, et al. Early metabolic acidosis in critically ill patients: a binational multicentre study. Crit Care Resusc 2021; 23: 67-75.
    10. Milnes SL, Mantzaridis Y, Simpson NB, et al. Values, preferences and goals identified during shared decision making between critically ill patients and their doctors. Crit Care Resusc 2021; 23: 76-85.
    11. Modra L, Pilcher D, Bailey M, Bellomo R. Sex differences in intensive care unit admissions in Australia and New Zealand. Crit Care Resusc 2021; 23: 86-93.
    12. Yi G, Deane AM, Ankravs M, Sharrock L, et al. A fixed dose approach to thrombosis chemoprophylaxis may be inadequate in heavier critically ill patients. Crit Care Resusc 2021; 23: 94-102.
    13. Higgins AM, Serpa Neto A, Bailey M, et al; PREDICT Study Investigators. The psychometric properties and minimal clinically important difference for disability assessment using WHODAS 2.0 in critically ill patients. Crit Care Resusc 2021; 23: 103-12.
    14. Datta R, Di Tanna GL, Youssef M, et al. An assessment of knowledge and education about sepsis among medical students: a multi-university survey. Crit Care Resusc 2021; 23: 117-8.
    15. Carr AC, Rowe S. Vitamin C and COVID-19: should clinical trials be prioritised for low income settings and vitamin C-deficient populations? Crit Care Resusc 2021; 23: 119-20.

The March 2021 issue of Critical Care and Resuscitation  has a strong focus on temperature with a study 1 that provides systematic evidence that non-invasive temperature measurements are spectacularly inaccurate, another assessing the possible differential effect of fluid bolus resuscitation in cardiac surgery patients with cold versus warm 20% albumin, 2 and a third reporting the efficacy of newer generation temperature control devices in controlling body temperature in febrile septic patients. 3 Reviewed in an editorial, 4 these studies make a compelling case for improving temperature management and monitoring in the intensive care unit (ICU).

Trials and large observational studies and their design, statistical analysis plan, and findings remain key components of CCR with reports from world-class studies. They include the much awaited Plasma-Lyte 148 versus Saline (PLUS) trial statistical analysis plan, 5 the results of the Fibrinogen Early In Severe Trauma studY (FEISTY), 6 the statistical analysis plan of the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart disease defects (NITRIC) trial 7 and the protocol of the international PeumoINSPIRE study of ICU nosocomial pneumonia. 8 No ICU journal in the world can publish such a strong ICU trials section in a single issue.

Finally, other articles in this issue address important aspects of the practice and epidemiology of critical illness in Australia and New Zealand: the prevalence and outcome of early metabolic acidosis, 9 shared decision making in the ICU, 10 sex differences among ICU admissions, 11 the inadequacy of fixed dose thrombosis chemoprophylaxis in heavier ICU patients, 12 the validation of the minimally clinically important difference for the World Health Organization Disability Score 2.0 (WHODAS 2.0), 13 the demonstration of inadequate knowledge about sepsis among medical students, 14 and the ongoing discussion about the optimal targeting of vitamin C therapy. 15

As Australia and New Zealand slowly emerge from the coronavirus disease 2019 (COVID-19) pandemic, CCR continues to provide the best of local and international research to help improve knowledge and practice in critical care.